The Wall Lab at Stanford University

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SysMed


Overview

We’ve developed a web application that provides you with the tools to visualize autism’s genetics. It contains a network of the genes linked to autism, and helps you to visualize the ways in which they interact. SysMed also provides methods for examining genes shared with other disorders.

Specific Aims

We seek to provide an easy-to-use resource that combines gene interaction and gene-disease association data on autism to enable network construction, visualization and comparison with other related neurological disorders. We hope to apply network thinking and cross-disease analysis to offer a dynamic picture of how autism genes interact within and between disorders and help to understand the complex genetic landscape of ASD.

Paper

Nelson TH, Jung JY, Deluca TF, Hinebaugh BK, St Gabriel KC, Wall DP. Autworks: a cross-disease network biology application for Autism and related disorders. BMC Med Genomics. 2012 Nov 28;5(1):56. Full text available.